NCT06884085

A Study to Compare to PK Characteristics and Safety Profiles Between AD-227 and Co-administration of AD-227A and AD-227B

An Open-label, Randomized, Single-dose, 2-sequence, 2-period, Crossover Study to Evaluate the Safety and Pharmacokinetics of AD-227 Compared to Co-administration of AD-227A and AD-227B in Healthy Adult Volunteers Under Fasting Conditions

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 70 (actual)
• Sponsor: Addpharma Inc. · Industry
• Sex: All
• Age: 19 Years
• Healthy volunteers: Accepted

Summary

Primary endpoint of this study is to evaluate the pharmacokinetic characteristics of AD-227 in healthy subjects.

Conditions

• Primary Hypertension

Interventions

Type	Name	Description
DRUG	Co-administration of AD-227A and AD-227B	Co-administration of AD-227A 1Tab. and AD-227B 1Tab., Per Oral
DRUG	Administration of AD-227	Administration of AD-227 1Tab., Per Oral

Timeline

• Start date: 2025-07-12
• Primary completion: 2025-08-13
• Completion: 2025-08-13
• First posted: 2025-03-19
• Last updated: 2025-12-01

Locations

1 site across 1 country: South Korea