NCT06880965

Effect of Concentrated Growth Factors on Short Implant-Supported Overdentures

Effect of Concentrated Growth Factors on Short Implant-Supported Overdentures: a Split-Mouth Design Study.

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: Tanta University · Academic / Other
• Sex: All
• Age: 20 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study will be to evaluate the effect of concentrated growth factors on stability and radiographic outcome of short implant supported mandibular assisted overdenture

Detailed description

A controlled clinical trial will be performed upon patients attending the outpatient clinic of Faculty of Dentistry Tanta University.Ten male patients will be selected for this study. Split mouth study design will be used in this study where, Group I represented the right side of the patients' mandibular posterior region will be restored with short implant in place of first molar and Group II represented the left side of the patients' mandibular posterior region will be restored with short implant in place of first molar and concentrated growth factors. The patients will receive partial mandibular assisted overdenture with O-ring attachment on the implant. Stability of implant and Radiographic evaluations will be carried out for every patient at regular recall visits at the time of insertion, 6 and 12 months

Conditions

• Partially Edentulous Patients

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	testing implant stability	testing implant stability by using the periotest device
DRUG	use concentrated growth factor.	short implants assisted over denture in combination with concentrated growth factor.
RADIATION	marginal bone loss calculation	marginal bone loss calculation by digitized periapical radiograph

Timeline

• Start date: 2023-08-24
• Primary completion: 2024-11-25
• Completion: 2024-12-04
• First posted: 2025-03-18
• Last updated: 2025-03-18

Locations

1 site across 1 country: Egypt

Regulatory

• FDA-regulated drug study
• FDA-regulated device study