NCT06880952

Effect of Post-operative Chlorhexidine on Postoperative Pain and Complications After Surgical Removal of Mandibular Third Molars

Effect of Post-operative Chlorhexidine on Postoperative Pain and Complications After Surgical Removal of Mandibular Third Molars: a Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 145 (actual)
• Sponsor: Isala · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This study aimed to assess the impact of postoperative chlorhexidine use on pain management following mandibular third molar removal In this prospective, randomized controlled trial,130 patients who underwent mandibular third molar surgical removal were divided into two groups: one group used chlorhexidine for postoperative rinsing and the other did not rinse. Pain levels, measured using the Numeric Rating Scale (NRS), were recorded daily for the first seven days post-surgery. Paired-samples t-tests were utilized for data analysis.

Conditions

• Third Molars Extraction

Interventions

Type	Name	Description
OTHER	Chlorhexidine Digluconate Mouthwash without Alcohol	In the rinsing group, the patients received a bottle of 0,2% chlorhexidine

Timeline

• Start date: 2021-09-01
• Primary completion: 2022-03-24
• Completion: 2022-08-19
• First posted: 2025-03-18
• Last updated: 2025-03-18

Locations

1 site across 1 country: Netherlands