NCT06880679

Ultrasound Acute Chest Syndrome Sickle Cell Disease

Use of Point-of-Care Ultrasound (POCUS) for the Diagnosis of Acute Chest Syndrome in Patients With Sickle Cell Disease

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: Indiana University · Academic / Other
• Sex: All
• Age: 25 Years
• Healthy volunteers: Not accepted

Summary

Feasibility and reliability of ultrasound in the inpatient hematology setting.

Detailed description

Acute chest syndrome (ACS) is a complication of sickle cell disease where individuals have symptoms of fever, low oxygen levels or difficulty breathing in the setting of a new lung finding on chest x-ray. Chest x-ray is a useful tool to identify it but has some side effects. The investigators think ultrasound will be an equally feasible, reliable tool and minimize some of the side effects associated with chest x-ray. Ultrasound is a non-invasive was to obtain an image that does not require radiation.

Conditions

• Acute Chest Syndrome
• Sickle Cell Disease

Interventions

Type	Name	Description
DEVICE	Point of Care Ultrasound	Point of Care Ultrasound during hospitalization

Timeline

• Start date: 2025-04-08
• Primary completion: 2026-06-30
• Completion: 2026-06-30
• First posted: 2025-03-18
• Last updated: 2026-04-09

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study