NCT06880614

Effect of Acute Protein Supplementation in Diabetic Patients

Effect of House Cricket Preload on Glycemic Response in Type 2 Diabetes Patients

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: University of Malaya · Academic / Other
• Sex: Male
• Age: —
• Healthy volunteers: Not accepted

Summary

The goal of this trial is to test the effect of house cricket (Acheta domesticus) preload on glycemic response in diabetic patients. The main question\[s\] it aims to answer are: whether house cricket powder could lower blood glucose spike and stimulate higher insulin response. Participants will consume either house cricket powder, whey protein isolate or placebo which will be mixed with a chicken-flavored soup. Participants fingers will be pricked for up to 2 hours. Researcher will compare house cricket powder with placebo to see if the glycemic response is better in house cricket supplemented group. Researcher will compare house cricket powder with whey protein isolate to see if both supplement induce comparable glycemic response.

Detailed description

Participants blood will be collected at 8 time points: Baseline 20 minutes after pre load 15 minutes after Oral Glucose Tolerance Test (OGTT) 30 minutes after OGTT 45 minutes after OGTT 60 minutes after OGTT 90 minutes after OGTT 120 minutes after OGTT

Conditions

• Diabetes Mellitus Type 2

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Oral Glucose Tolerance test (75g 2-hour)	The participants are required to drink a glucose solution containing 75 g of glucose dissolved in 250 mL of water
DIETARY_SUPPLEMENT	Whey	Supplemented with whey protein isolate masked with a chicken-flavored soup
DIETARY_SUPPLEMENT	House cricket	Supplemented with house cricket powder masked with chicken-flavored soup
DIETARY_SUPPLEMENT	Placebo	Placebo consists of chicken-flavored soup without any supplement inside

Timeline

• Start date: 2025-06-01
• Primary completion: 2025-12-01
• Completion: 2025-12-01
• First posted: 2025-03-17
• Last updated: 2025-12-09

Locations

1 site across 1 country: Malaysia