NCT06879821

High-intensity Functional Training on Functional and Cognitive Performance in People with Parkinson's Disease.

Effectiveness of a High-intensity Functional Training (HIFT) Program on Functional and Cognitive Performance in People with Parkinson's Disease.

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 34 (estimated)
• Sponsor: Fundacion Para La Investigacion Hospital La Fe · Academic / Other
• Sex: All
• Age: 40 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Parkinson's disease (PD) is a progressive and chronic neurodegenerative disease, which presents signs and symptoms both motor (impaired gait, posture, balance, etc.) and cognitive (memory loss, dementia, etc.), all of which are causing disability and assuming a high economic cost. Currently, there are already certain authors who have shown how a high-intensity interval training (HIIT) protocol produces improvements in cognitive and physical performance in healthy adults6 and in people with multiple sclerosis. However, another modality has been created, such as high-intensity functional training (HIFT), which can benefit different populations, both healthy and pathological, due to the multimodal nature of the exercises. Thanks to multimodality, more aspects such as agility, coordination and precision of movements are worked on compared to unimodal HIIT programs that make this relevant work difficult in a person's daily life. The current study aims to demonstrate the effectiveness of a HIFT training protocol in a specific population, such as people with Parkinson's disease.

Detailed description

The hypothesis is that high-intensity functional training (HIFT), at a motor and cognitive level, provides a greater benefit than conventional programs of strength, balance and cognition, on the functionality and cognitive capacity of people with Parkinson's disease. Overall objective: \- To assess whether the HIFT training program is associated with significant improvements in functional and cognitive capacity compared to conventional strength, balance and cognition programs in Parkinson's patients. Secondary objectives: 1. To assess whether the HIFT program improves the quality of life in patients with PD. 2. To study whether the HIFT program reduces the degree of dependency of patients with PD. 3. To determine if the HIFT program improves physical performance in patients with PD 4. To assess whether the HIFT program reduces the risk of falls in patients with PD. 5. To investigate whether the HIFT program improves balance in patients with PD. 6. To determine if the HIFT program improves functional capacity in patients with PD. 7. To study whether the HIFT program improves cognitive function in patients with PD

Conditions

• Parkinson Disease

Interventions

Type	Name	Description
OTHER	high intensity functional training	The pillar of rehabilitation will be based on high intensity functional training. 45-minute sessions divided into 5 minutes of warm-up, 35 minutes of functional exercises, and 5 minutes of going back to bed and cooling down. The 35 minutes of exercises were divided into 3 categories: lower extremity exercises, upper extremity exercises, and static and dynamic coordination and balance exercises. Each category will consist of 3 exercises per session, performing 2-3 series with a maximum of repetitions of 10-RM. The progression of the load will be progressively increased in weeks 3, 5 and 8 between 40-60% of the 1-RM.

Timeline

• Start date: 2022-03-14
• Primary completion: 2022-11-30
• Completion: 2025-04-30
• First posted: 2025-03-17
• Last updated: 2025-03-17

Locations

1 site across 1 country: Spain