NCT06878378

Risk Factors for Inadequate Bowel Preparation Before Colonoscopy

Identification of Risk Factors for Inadequate Bowel Preparation Before Colonoscopy and Construction of a Predictive Model: a Nationwide Multicenter Prospective Study

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 10,000 (estimated)
• Sponsor: Changhai Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The primary objectives of this study are twofold: Firstly, to investigate the current status of bowel preparation protocols and their quality across hospitals at various levels in China, particularly following the release of the updated 2023 bowel preparation guidelines. This aims to standardize and optimize bowel preparation protocols nationwide. Secondly, to identify and analyze risk factors contributing to suboptimal bowel preparation quality in patients undergoing colonoscopy. The study will examine the correlation between these factors and bowel preparation scores, establish a risk prediction model for preparation failure, and provide a theoretical foundation for developing personalized bowel preparation regimens tailored to individual patient characteristics.

Detailed description

The project is divided into three key phases: 1. Initiation Phase: Develop a Bowel Preparation Assessment Questionnaire (BPAQ) to standardize data collection. Establish collaborative centers (multicenter hospitals) nationwide for coordinated implementation. 2. Implementation Phase: Conduct on-site audits to evaluate bowel preparation practices across participating centers. Deliver protocol-specific training to healthcare providers, emphasizing compliance with the 2023 guidelines. Systematically collect bowel preparation data, including patient demographics, protocol adherence metrics, and clinical outcomes. 3. Conclusion Phase: Prioritize data quality assurance through dual-entry validation and logic checks to ensure authenticity, comprehensiveness, and objectivity. Generate consolidated reports to identify systemic gaps and propose evidence-based optimization strategies.

Conditions

• Colonoscopy
• Colonoscopy: Bowel Preparation

Interventions

Type	Name	Description
OTHER	Investigation of Factors Influencing Bowel Preparation Quality	Observed parameters include BMI, history of abdominal surgery, history of diabetes, history of diarrhea and constipation, stool characteristics, and specific bowel preparation protocols.

Timeline

• Start date: 2025-02-21
• Primary completion: 2026-02-01
• Completion: 2026-02-01
• First posted: 2025-03-17
• Last updated: 2025-03-18

Locations

1 site across 1 country: China