NCT06878235

Validation of the French Version of the Primary Lateral Sclerosis Functioning Rating Scale (PLSFRS)

Validation of the French Version of the PLSFRS Scale

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 80 (estimated)
• Sponsor: University Hospital, Tours · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This is a national, multicentric, prospective, descriptive study evaluating the psychometric properties of the French version PLSFRS scale

Detailed description

This is a prospective study conducted in 8 French ALS centers which will enroll 80 patients with PLS. All these patients will undergo an evaluation of their functional status from the ALSFRS-r and PLSFRS scales. All patients will be evaluated at 3 time points (T0,M6 at the outpatient clinic) and at M3 remotely. The aim of the study will be to validate a trans-cultural and psychometric version of the PLSFRS available for the French PLS population.

Conditions

• Lateral Sclerosis

Interventions

Type	Name	Description
OTHER	Assessment of the functional status	assessment of their functional status using the French version of the PLSFRS scale during a routine multidisciplinary assessment every 3-6 months for all patients with motor neurone disease, as recommended by the FILSLAN network

Timeline

• Start date: 2025-04-11
• Primary completion: 2025-12-01
• Completion: 2026-06-01
• First posted: 2025-03-14
• Last updated: 2025-05-29

Locations

7 sites across 1 country: France