NCT06877572

Weight Loss Management in Endometrial Cancer Survivors

Enacting Active Survivorship: Implementation of Weight Management Strategies in Endometrial Cancer Survivors

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 50 (estimated)
• Sponsor: University of Kansas Medical Center · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study is being done to understand how oncologists can engage a multidisciplinary team to help endometrial cancer survivors with obesity to engage in a weight management program and potentially start a weight loss medication. Obesity often impacts the future health and longevity of early-stage endometrial cancer survivors more than their cancer diagnosis. Patients will be referred to the KUMC OB/Gyn weight management clinic to discuss weight management options. * If patients decide to use medications for weight loss, then the study will collect data from their chart that is recorded as part of routine monitoring for patients on weight loss medications. * If patients decide not to use any medications, the study will monitor physical exam and lab data collected as part of their routine medical care. The study will also try to understand reasons why patients did or did not start using a weight loss medication.

Conditions

• Endometrial Cancer Survivors
• Weight Management
• Early Stage Endometrial Cancer

Interventions

Type	Name	Description
BEHAVIORAL	Weight loss with pharmacotherapy	Patients will meet with a weight management specialist and discuss their options for weight loss including medications (GLP-1 agonist, naltrexone/bupropion, orlistat, or phentermine/topiramate) or bariatric surgery.
BEHAVIORAL	Weight loss without pharmacotherapy	Participants not on medications will have their weight recorded at subsequent cancer surveillance or other routine medical visits

Timeline

• Start date: 2025-03-25
• Primary completion: 2028-10-01
• Completion: 2030-10-01
• First posted: 2025-03-14
• Last updated: 2025-10-27

Locations

1 site across 1 country: United States