Trials / Enrolling By Invitation
Enrolling By InvitationNCT06872775
855303-RNA Biomarker Validation
A Multi-Center Observational Study to Validate RNA-Biomarkers as Prognostic of Fracture Healing
- Status
- Enrolling By Invitation
- Phase
- —
- Study type
- Observational
- Enrollment
- 110 (estimated)
- Sponsor
- University of Pennsylvania · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to test the accuracy of using RNA in blood as a way to forecast new fracture healing outcome.
Detailed description
This study will follow a registry + biospecimen collection format. Subjects will be enrolled at participating Sites as they present for care for new traumatic appendicular skeletal fractures (0 - ≤7 Days post-injury) and will provide blood specimens for study analysis and future use at up to 4 post-injury windows of treatment (i.e., Window 1, 0 - ≤7 Days; Window 2, 8 - ≤14 days; Window 3, 15 - ≤42 Days; and Window 4, 43 - ≤84 Days post-injury).
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Blood draws to assess RNA expression levels | None. Standard of Care (SOC) only. |
Timeline
- Start date
- 2025-08-25
- Primary completion
- 2028-08-24
- Completion
- 2028-08-24
- First posted
- 2025-03-12
- Last updated
- 2026-01-16
Locations
7 sites across 1 country: United States
Source: ClinicalTrials.gov record NCT06872775. Inclusion in this directory is not an endorsement.