NCT06870201

Iron Absorption From Lipid-Based Nutrient Supplements

Dietary Iron Absorption From Lipid-Based Nutrient Supplements - A Pilot Study

• Status: Active Not Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 30 (estimated)
• Sponsor: Pennington Biomedical Research Center · Academic / Other
• Sex: All
• Age: 1 Year – 3 Years
• Healthy volunteers: Accepted

Summary

The overall objective of this study is to determine dietary iron absorption from lipid-based nutrient supplements (LNS) in apparently healthy and undernourished children. This case-control study will recruit apparently healthy children and children with uncomplicated undernutrition (age 1-3 years, n=15/group) from Msambweni and the surrounding rural communities in Kwale County, Kenya. At the baseline visit (day 0), participants will be provided with an LNS labeled with a stable iron isotope (57-Fe). Participants will return to the hospital 14 days later (day 14) for a blood draw. Blood collected on day 14 will be used to measure iron isotope incorporation into red blood cells. Blood collected at screening will be used to measure indicators of anemia, iron status, hepcidin, and inflammation.

Conditions

• Undernutrition
• Healthy

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Lipid-Based Nutrient Supplement	LNS labeled with a stable iron isotope

Timeline

• Start date: 2025-03-25
• Primary completion: 2026-03-01
• Completion: 2026-03-01
• First posted: 2025-03-11
• Last updated: 2025-12-05

Locations

1 site across 1 country: Kenya