NCT06869837

EOIPB in Laparoscopic Cholecystectomy: Impact on Opioid Consumption Guided by ANI and Analgesia Quality

Effects of External Oblique Intercostal Plane Block Applied in Laparoscopic Cholecystectomy Surgery on Intraoperative Opioid ConsumptionDetermined by ANI (Analgesia Nociceptive Index) and Postoperative Analgesia Quality Guide; A Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (actual)
• Sponsor: Samsun University · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The aim of the study was to evaluate the response of regional anesthesia to remifentanyl consumption in patients undergoing laparoscopic cholecystectomy surgery.

Detailed description

Routine anesthesia and analgesia protocol will be applied to all participants. The study aims to evaluate the remifentanyl consumption of the participants by dividing them into two groups as those with and without block and then performing their monitoring (pulse, mean arterial pressure with noninvasive measurement, oxygen saturation, Analgesia Nociception Index, Bispectral index). Remifentanil level will be adjusted according to the ANI value. The target is to keep the ANI between 50-70.

Conditions

• Pain Management
• Laparoscopic Cholecystectomy Surgery

Interventions

Type	Name	Description
OTHER	Group EOİPB	Bilateral external oblique intercostal plane block under USG guidance will be applied 45 minutes before cholecystectomy surgery.

Timeline

• Start date: 2025-04-08
• Primary completion: 2025-12-15
• Completion: 2025-12-20
• First posted: 2025-03-11
• Last updated: 2026-01-06

Locations

1 site across 1 country: Turkey (Türkiye)