Clinical Trials Directory

Trials / Not Yet Recruiting

Not Yet RecruitingNCT06869304

The Effect of Steep Trendelenburg Position on Neurocognitive Functions in Robotic Radical Prostatectomy Cases

Examining the Effect of Steep Trendelenburg Position on Neurocognitive Functions With MoCA Test in Robotic-assisted Radical Prostatectomy Surgeries.

Status
Not Yet Recruiting
Phase
Study type
Observational
Enrollment
56 (estimated)
Sponsor
Ankara City Hospital Bilkent · Academic / Other
Sex
Male
Age
65 Years – 100 Years
Healthy volunteers
Accepted

Summary

The aim of this study is to evaluate the effects of the steep Trendelenburg position in robotic prostatectomy cases, where anesthesia depth is monitored using BIS and cerebral perfusion is tracked with NIRS, and to determine the incidence of neurocognitive dysfunction using the MoCA test in the postoperative period. Steep Trendelenburg position and CO₂ pneumoperitoneum during robotic radical prostatectomy lead to significant changes in intracranial pressure and cerebral oxygenation, which may contribute to postoperative neurocognitive dysfunction (POCD). Monitoring anesthesia depth with Bispectral Index (BIS) and cerebral perfusion with Near-Infrared Spectroscopy (NIRS) may help detect early neurocognitive changes, and MoCA test assessments will reveal a measurable decline in cognitive function postoperatively.

Conditions

Interventions

TypeNameDescription
DIAGNOSTIC_TESTMontreal Cognitive AssessmentPreoperative and postoperative MoCA test scores

Timeline

Start date
2025-03-15
Primary completion
2025-04-15
Completion
2025-10-30
First posted
2025-03-11
Last updated
2025-03-11

Locations

1 site across 1 country: Turkey (Türkiye)

Source: ClinicalTrials.gov record NCT06869304. Inclusion in this directory is not an endorsement.