NCT06868368

Perceptions of Vaping Products

Perceptions of Vaping Products Among Young Adults

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 53 (actual)
• Sponsor: Ohio State University Comprehensive Cancer Center · Academic / Other
• Sex: All
• Age: 21 Years – 34 Years
• Healthy volunteers: Accepted

Summary

This clinical trial studies the effects, appeal, and abuse liability of 6-methyl nicotine (metatine) electronic cigarettes among young adults.

Detailed description

PRIMARY OBJECTIVES: I. Assess the pharmacokinetics of metatine and nicotine electronic (e)-cigarettes. II. Assess the abuse liability and appeal of commercial e-cigarettes containing metatine versus nicotine. III. Determine the impact of metatine on e-cigarette puffing behavior (topography). OUTLINE: Participants attend 3 sessions where they will be randomized to 1 of 3 types of e-cigarette. Participants will use the e-cigarette ad-libitum for 30 minutes and answer survey questions about their perceptions of the e-cigarette. Participants must also undergo 4 blood draws during the vaping session.

Conditions

• Abuse Tobacco
• Exposure

Interventions

Type	Name	Description
OTHER	Biospecimen Collection	Undergo blood sample collection
OTHER	Survey Administration	Complete Surveys
BEHAVIORAL	Vaping Topography	Use e-cigarette connected to a topography device
OTHER	Participant's Own Preferred E-cigarette	Participant vapes their own preferred e-cigarette for 30 minutes
OTHER	Nicotine E-cigarette	Participant vapes a commercially available nicotine e-cigarette for 30 minutes
OTHER	6-methyl-nicotine (metatine) e-cigarette	Participant vapes a commercially available metatine e-cigarette for 30 minutes

Timeline

• Start date: 2025-03-03
• Primary completion: 2025-11-04
• Completion: 2025-11-04
• First posted: 2025-03-10
• Last updated: 2025-12-22

Locations

1 site across 1 country: United States