NCT06868225

Scientific Rationale and Design for a Prospective Study to Codify Coronary Lesions Based on Fluid Mechanics and Acoustic Mechanisms

Prospective Study to Codify Coronary Lesions Based on Fluid Mechanics and Acoustic Mechanisms

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: Tan Tao University, School of Medicine · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

From January 2020 to June 2025, patients coming to the cardiac catheterization laboratories (CCL) for out-patient coronary angiography with diagnosis of unstable angina were screened for inclusion. Patients were included in the study if they had previously undergone one or more coronary angiograms, allowing for a longitudinal comparison of dynamic flow and phenomena between the two or more angiograms.

Detailed description

Patients with history of prior percutaneous coronary intervention (PCI), coronary artery bypass graft surgery (CABG) were excluded. The aortic stenosis patients were also excluded if they had end-stage disease with survival time \<6 months or if they had other severe hemodynamic disturbances such as hypotension from non-cardiac problems (sepsis, bleeding, etc).

Conditions

• Unstable Angina (UA)

Timeline

• Start date: 2025-04-20
• Primary completion: 2025-07-30
• Completion: 2025-08-30
• First posted: 2025-03-10
• Last updated: 2025-04-17