NCT06867263

Outcomes of Posterior Urethral Valve Fulguration

Long-term Evaluation of Patients With Fulguration of Posterior Urethral Valve: A Retrospective Cohort Study

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 35 (estimated)
• Sponsor: Assiut University · Academic / Other
• Sex: Male
• Age: —
• Healthy volunteers: —

Summary

To evaluate the long-term outcome after fulguration of the posterior urethral valve.

Detailed description

Posterior Urethral Valves (PUV) are the most common cause of lower urinary tract obstruction. More severe forms are detected early in pregnancy (mainly type I), while other forms are usually discovered later in childhood when investigating lower urinary tract symptoms. Bladder dysfunction is common and is associated with urinary incontinence in about 55% (0%-72%). Despite the removal of the obstruction by urethral valve ablation, pathological changes in the urinary tract can occur with progressive bladder dysfunction, which can cause deterioration of the upper urinary tract as well. For this reason, all children with PUV require long-term follow-up, always until puberty. In many cases, the life-long current status is uncertain. The current literature lacks research on long-term outcomes.

Conditions

• Posterior Urethral Valve

Interventions

Type	Name	Description
PROCEDURE	Fulguration	Posterior urethral valve fulguration

Timeline

• Start date: 2025-05-01
• Primary completion: 2027-05-01
• Completion: 2027-07-01
• First posted: 2025-03-10
• Last updated: 2025-03-10