NCT06862375

Weight Loss Through Mayo Clinic Diet

Weight Loss Through Mayo Clinic Diet; a Prospective Pilot Study

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 250 (estimated)
• Sponsor: Mayo Clinic · Academic / Other
• Sex: All
• Age: 18 Years – 64 Years
• Healthy volunteers: Accepted

Summary

The purpose of study is to evaluate the efficacy of the Mayo Clinic Diet in clinically significant weight loss (\>5%) versus usual care. We also wish to evaluate the feasibility, barriers to completion, and sustainability of this intervention at the 24, and 52-week marks. Lastly, we aim to study the change in participants body composition and quality of life at the end of this intervention.

Conditions

• Obesity

Interventions

Type	Name	Description
BEHAVIORAL	Mayo Clinic Diet	Subjects will utilize their choice of the following resources for 12 weeks: * Mayo Clinic Diet book, 3rd Edition * Digital Wellness app subscription * Both the Mayo Clinic Diet book and Digital Wellness app
BEHAVIORAL	Usual Care	Subjects will be given the 'Eat Well Use the Plate' informational hand-out, as well as a list of food, physical activity and weight tracking apps to be utilized as resources for self-monitoring .

Timeline

• Start date: 2025-03-05
• Primary completion: 2027-03-01
• Completion: 2028-03-01
• First posted: 2025-03-06
• Last updated: 2025-10-07

Locations

1 site across 1 country: United States