NCT06853600

Effects of Rhodiola Rosea Supplementation on Mental Fatigue, Visuo-cognitive Processing, and Strength Performance

Optimización Del Rendimiento Durante el Entrenamiento de Fuerza a través de implementación Aguda de suplementación Nutricional

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 25 (actual)
• Sponsor: Universidad de Granada · Academic / Other
• Sex: All
• Age: 18 Years – 40 Years
• Healthy volunteers: Accepted

Summary

This document aims to provide information to request authorization to collect data on the effects of supplementation administered 30 minutes before resistance training on the number of repetitions, execution speed, and perceived effort for the bench press and bench pull exercises. To grant authorization, an informed consent form must be signed for the use of the information. If authorization is granted, personalized information will be provided by the professional requesting the consent. It is recommended to read this document beforehand and ask any questions necessary to understand the details. If desired, the document can be taken for consultation with others, allowing ample time to make a decision. The decision is entirely voluntary. It is possible to decline authorization for the use of personal and/or health data without affecting the relationship with the professional requesting the consent or healthcare services. PURPOSE OF THIS REQUEST Participation involves attending a total of 5 sessions. The study begins with a familiarization session, which includes measurements of weight, height, and the determination of the 20-repetition maximum load (i.e., the maximum load that can be lifted between 18-22 times), which will be used in the rest of the experimental sessions. In the experimental sessions, a supplement capsule will be administered 30 minutes before starting the resistance training. The composition of the capsule will not be disclosed to ensure a triple-blind approach for participants and evaluators. The resistance training will consist of 4 supersets (each superset consisting of two exercises: bench press and bench pull). There will be 5-minute breaks between each superset and 1.5-minute breaks between the two exercises within the same superset. During the supersets, the maximum number of repetitions will be performed until reaching muscle failure. Heart rate and blood pressure will be measured during the training, and perceived effort will be recorded. No physiological samples will be collected. This study aims to provide a clearer understanding of which supplement may have the most beneficial effects when training with light loads and repetitions to failure in a superset, a topic that has not been explored before. REQUEST DETAILS The professional attending to this study is Amador García Ramos. By signing this document, authorization is given to complete questionnaires about perceived effort. POTENTIAL BENEFITS AND RISKS No specific benefits or risks are expected. Participation will contribute to increasing scientific knowledge. No compensation will be provided for authorizing the use of health data. Additionally, the researchers involved in this project will not receive specific compensation for their participation in the study.

Detailed description

The current study is a randomized, placebo-controlled, triple-blind (participants, researchers, and data analysts), and crossover experimental trial. Participants visit the laboratory on five occasions separated by seven days: one preliminary testing session and four experimental sessions. During the preliminary testing session, participants are introduced to the Stroop and MOT tests, followed by the determination of 1RM loads for the bench press and bench pull exercises. The four experimental sessions follow the same protocol, differing only in the supplement (Rhodiola Rosea \[RR\] or placebo) and mental task conditions (Stroop test or control video). Participants are counterbalanced and assigned to each experimental session condition using the Research Randomizer online software (www.randomizer.org): (I) RR and Stroop test, (II) RR and control video, (III) placebo and Stroop test, and (IV) placebo and control video. The assessment order in each experimental session is as follows: (I) mental task condition (Stroop test or control video), (II) MOT pre-training, (III) strength training, and (IV) MOT post-training. All sessions are conducted on the same day of the week and at consistent times (±1 hour) for each participant. Participants are instructed to avoid stimulants on the testing day and refrain from resistance exercise 24 hours before the visit.

Conditions

• Sport Medicine

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Rhodiola Rosea Capsules	One of the most practical and accessible options for mitigating the occurrence of mental fatigue is the strategic use of nutritional supplements. Several nutritional supplements have been shown to reduce behavioural or subjective markers of mental fatigue, including caffeine, creatine, panax ginseng, and various vitamins or minerals. Among these, Rhodiola Rosea (RR), a supplement with purported adaptogenic and ergogenic properties, has gained attention. Several randomized controlled trials have reported reductions in mental fatigue after RR supplementation without adverse effects. The main objective of this study was to explore the effects of four days of Golden Root Extract (RR) supplementation on mental fatigue, visuo-cognitive processing, strength performance, and perceived exertion in young, healthy individuals.

Timeline

• Start date: 2024-05-25
• Primary completion: 2024-08-30
• Completion: 2024-09-15
• First posted: 2025-03-03
• Last updated: 2025-03-03

Locations

1 site across 1 country: Spain