NCT06853249

Influence of Food Texture on Appetite Control, Gastric Emptying, and Energy Expenditure

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: University of Kiel · Academic / Other
• Sex: All
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

The aim of the study is to investigate the effect of liquid versus semi-solid meals on the regulation of energy balance in healthy young adults.The main questions it aims to answer are: * Does a protein-rich liquid meal result in less satiety and therefore higher ad libitum energy intake at the next meal than an isocaloric oatmeal with the same macronutrient ratio? * Is the consumption of a protein-rich liquid meal as a beverage in addition to an ad libitum oatmeal less compensated within the meal and at the next meal and provides thus a higher ad libitum energy intake than an isovolumetric noncaloric soft drink in addition to an ad libitum oatmeal? Researchers will compare a protein-rich liquid meal to an isocaloric oatmeal with matched macronutrient composition to answer the first question. Researchers will compare a protein-rich liquid meal + oatmeal to a noncaloric softdrink (water with sucralose and flavoring) + oatmeal to answer the second question. Participants will: * spend 4 intervention days in a metabolic chamber (whole room indirect calorimeter) * consume pre-definied preloads for breakfast and ad libitum lunch meals on 4 intervention days

Conditions

• Nutrition
• Healthy Male and Female Subjects

Interventions

Type	Name	Description
OTHER	liquid meal	An isocaloric amount (500 kcal) of a commercially available liquid meal with a matched macronutrient composition is consumed. After 5 hours, lunch is eaten ad libitum.
OTHER	semi-solid meal	An isocaloric amount (500 kcal) of a commercially available semi-solid oatmeal with a matched macronutrient composition is consumed. After 5 hours, lunch is eaten ad libitum.
OTHER	caloric drink + semi-solid meal	A predefined amount of a caloric drink (= liquid meal) together with an ad libitum amount of a semi-solid meal is consumed. After 5 hours, lunch is eaten ad libitum.
OTHER	non-caloric drink + semi-solid meal	A predefined amount of a non-caloric drink (= water, sucralose, flavor) together with an ad libitum amount of a semi-solid meal is consumed. After 5 hours, lunch is eaten ad libitum.

Timeline

• Start date: 2025-04-01
• Primary completion: 2025-12-01
• Completion: 2026-03-01
• First posted: 2025-02-28
• Last updated: 2025-04-11

Locations

1 site across 1 country: Germany