Trials / Active Not Recruiting
Active Not RecruitingNCT06850896
Antibiotic Exposure on Gut Microbiota and Motility Establishment in Newborns
Effects of Early Antibiotic Exposure on Gut Microbiota and Motility Establishment in Newborns: a Prospective Cohort Study
- Status
- Active Not Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 200 (estimated)
- Sponsor
- The First Hospital of Jilin University · Academic / Other
- Sex
- All
- Age
- 24 Weeks – 36 Weeks
- Healthy volunteers
- Not accepted
Summary
This prospective cohort study aims to investigate the impact of early antibiotic exposure on the establishment of gut microbiota and motility in newborns, particularly preterm infants. The study will explore the correlation between antibiotic exposure, gut microbiota colonization, and 5-hydroxytryptamine (5-HT) levels, which are critical for gastrointestinal motility. The findings may provide insights into optimizing antibiotic use and improving gastrointestinal health in neonates.
Conditions
Timeline
- Start date
- 2025-02-01
- Primary completion
- 2027-05-30
- Completion
- 2027-05-30
- First posted
- 2025-02-28
- Last updated
- 2025-02-28
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT06850896. Inclusion in this directory is not an endorsement.