NCT06848998

Exercise and Cognition Among Stroke Survivors

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 24 (actual)
• Sponsor: Leeds Beckett University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study aimed to: (1) identify a suitable cardiopulmonary exercise testing protocol for people with moderate to severe movement impairments after stroke by investigating the safety and feasibility of delivering two methods of CPET modes: treadmill with body-weight support (TBWS) and cycle ergometry (CE); and (2) explore the safety and feasibility of a delivering a 6-week exercise-based intervention or people with moderate to severe movement impairments after stroke, with a view to improve cognitive health.

Conditions

• Aerobic Exercise
• Resistance Exercise

Interventions

Type	Name	Description
BEHAVIORAL	aerobic exercise	40 minutes of aerobic exercise, twice per week for six weeks. Sessions comprised of the following: 10-minute warm-up, 40-minute conditioning period as a circuit, and 10-minute cool-down. Aerobic exercises (for example, recumbent cycling, stepping, arm crank) commenced at an intensity of 40-50% heart rate reserve (HRR) and increased incrementally by 10% as tolerated, up to a maximum of 70-80%. All sessions were individually tailored as far as possible to participants' needs, abilities, and preferences.
BEHAVIORAL	Resistance exercise	4 x resistance exercises (3 sets of 6 repetitions), twice per week for six weeks. Strengthening exercises (for example, resistance band work) were prescribed at an intensity that corresponded to 11-12 and incrementally increased to a maximum of 14-15, as tolerated, on the Borg Ratings of Perceived Exertion (RPE) 6-20 Scale. All sessions were individually tailored as far as possible to participants' needs, abilities, and preferences.

Timeline

• Start date: 2018-04-19
• Primary completion: 2019-07-31
• Completion: 2020-07-30
• First posted: 2025-02-27
• Last updated: 2025-02-27

Locations

1 site across 1 country: United Kingdom