NCT06847594

An Evaluation the Effect of Superhydration Versus Dextrose 10% for Prevention of Post Operative Nausea and Vomiting After Laparoscopic Cholecystectomy (Prospective Randomised Controlled Study)

Superhydration Versus Dextrose 10% for Prevention of Post Operative Nausea and Vomiting After Laparoscopic Cholecystectomy (Prospective Randomised Controlled Study)

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 204 (actual)
• Sponsor: Ain Shams University · Academic / Other
• Sex: All
• Age: 21 Years – 60 Years
• Healthy volunteers: Accepted

Summary

The goal of this clinical trial is to learn if Dextrose 10% or superhydration works to prevent postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy. . The main questions it aims to answer are: Does Dextrose 10% or superhydration lower the number of times participants gets an episode of nausea and vomititng after laparoscopic cholecystectomy surgery? Researchers will compare Dextrose 10% versus superhydration to a placebo (a look-alike substance that contains no drug) to see if glucose 10% or superhydation can work to prevent postoperative nausea and vomiting. Participants will: Take Dextrose 10% or superhydration or a placebo in the operation monitored for 4 hours after surgery to check on their nausea and vomiting state

Conditions

• Postoperative Nausea and Vomiting (PONV)

Interventions

Type	Name	Description
DRUG	ringer lactate (20ml/kg)	ringer lactate 20 ml/kg over the first 90 to 120 minutes after induction intraoperatively
DRUG	Dextrose 10%	Dextrose 10% 250 ml over 60 minutes

Timeline

• Start date: 2024-02-25
• Primary completion: 2024-09-25
• Completion: 2024-10-10
• First posted: 2025-02-26
• Last updated: 2025-02-26

Locations

1 site across 1 country: Egypt