NCT06845579

Prediction of Blood Pressure Outcomes Following Renal Denervation (PREDICT-RDN)

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 90 (estimated)
• Sponsor: Heart Center Leipzig - University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Prospective, single arm trial to assess the effects of renal denervation on day-by-day blood pressure measurements and time in blood pressure target range, as well as establish a multivariate prediction model for blood pressure reduction after renal denervation.

Conditions

• Uncontrolled Arterial Hypertension

Interventions

Type	Name	Description
PROCEDURE	Renal sympathetic denervation	All procedures will be carried out by highly experienced interventional cardiologists, each having performed a minimum of 20 RDN prior to treating study patients. All interventions will be performed with the CE-marked Symplicity SpyralTM (Medtronic, Minneapolis, MN, USA) renal denervation system following current treatment standards. Procedures will be performed as stated in the IFU. The specific ablation points will be determined by the discretion of the interventionalist.

Timeline

• Start date: 2025-06-01
• Primary completion: 2027-02-28
• Completion: 2028-02-29
• First posted: 2025-02-25
• Last updated: 2025-06-24

Locations

2 sites across 1 country: Germany