NCT06843538

Peri-operative Tamsulosin and Impact on Voiding Trial After Same-day Urogynecology Surgery

Peri-operative Tamsulosin and Impact on Voiding Trial Following Outpatient Urogynecology Surgery: a Randomized Controlled Trial

• Status: Recruiting
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 166 (estimated)
• Sponsor: TriHealth Inc. · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this research study is to determine if taking tamsulosin preoperatively decreases your chances of being discharged after surgery with a Foley catheter (flexible tube that drains urine from the bladder into a collection bag).

Conditions

• Postoperative Urinary Retention (POUR)

Interventions

Type	Name	Description
DRUG	Tamsulosin	This intervention will investigate if tamsulosin will decrease postoperative urinary retention. Subjects will be directed to start taking the medication 5-7 days prior to their procedure; as previous studies have shown, this is when tamsulosin reaches its steady state. Patients will continue to take their assigned pills for 7 days postoperatively.
DRUG	Placebo	This intervention will ensure blinding and an accurate measure of the real effect of tamsulosin.

Timeline

• Start date: 2025-02-03
• Primary completion: 2026-02-01
• Completion: 2026-06-01
• First posted: 2025-02-25
• Last updated: 2025-02-25

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study