NCT06842290

Effect of Botulinum Toxin a Injection in Treatment of Recession RT1 and RT2

Effect of Botulinum Toxin -A Injection in Mentalis Muscle with Coronally Advanced Flap and De-epithelized Free Gingival Graft in Treatment of RT1 , RT2 Gingival Recession _Randomized Control Trial

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 28 (estimated)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this study type: clinical trial\] is to learn the effect of Botulinum Toxin \_A injection in treatment of RT1andRT2 Gingival recession in lower anterior teeth . Primary outcome is keratinzed tissue width. Researchers will compare Coronally Advanced flap with De-epithelized free gingival graft and Botulinum toxin-A injection in Mentalis muscle with coronally advanced flap with De-epithelized free gingival graft alone . The outcome will be measured at baseline, after 3 months and after 6 mobths \_medical history * 3 mm horizontal incisions, then two vertical incisions * deepitheliztion of anatomical papillae * superficial and deep incisions * harvesting DFGG * Suturing * BOTOX injection

Conditions

• Gingival Recession

Interventions

Type	Name	Description
PROCEDURE	Botulinum toxin-A injection	Botulinum toxin-A Injection Mentalis muscle in lower anterior teeth
PROCEDURE	Coronally advanced flap	Coronally Advanced Flap andDe-epithelized Free Gingival Graft

Timeline

• Start date: 2025-04-04
• Primary completion: 2026-10-16
• Completion: 2026-10-16
• First posted: 2025-02-24
• Last updated: 2025-02-25