NCT06841731

A Trial of HRS-8427 in the Treatment of Adults With Bacterial Pneumonia

A Multi-center, Randomized, Double-blind, Active Controlled, Parallel Groups, Phase II Study to Evaluate the Efficacy and Safety of HRS-8427 in the Treatment of Adults With Hospital-acquired Bacterial Pneumonia (HABP) or Ventilator-associated Bacterial Pneumonia (VABP)

• Status: Recruiting
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Jiangsu HengRui Medicine Co., Ltd. · Industry
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to evaluate the efficacy and safety of HRS -8427 in patients with HABP/VABP.

Conditions

• Hospital-acquired Bacterial Pneumonia (HABP)
• Ventilator-associated Bacterial Pneumonia (VABP)

Interventions

Type	Name	Description
DRUG	HRS-8427	HRS-8427 for injection.
DRUG	Meropenem	Meropenem for injection.

Timeline

• Start date: 2025-04-03
• Primary completion: 2026-02-01
• Completion: 2026-02-01
• First posted: 2025-02-24
• Last updated: 2025-04-22

Locations

1 site across 1 country: China