NCT06841692

Diuretic Testing in Chronic Kidney Disease

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 86 (estimated)
• Sponsor: Erasmus Medical Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The goal of this clinical trial is to predict the progression of chronic kidney disease by diuretic testing in patients with chronic kidney disease. The main questions it aims to answer are: Does a worse result of a diuretic test predict the progression of chronic kidney disease? If there is a comparison group: Researchers will compare the diuretic test in patients with chronic kidney disease to healthy participants to see if the results are different in a healthy kidney. Participants will undergo diuretic testing. This involves the administration of bumetanide and hydrochlorothiazide with subsequent blood and urine collections.

Conditions

• Kidney Disease, Chronic

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Diuretic Testing	The administration of hydrochlorothiazide and bumetanide is used to stimulate and assess tubular function.

Timeline

• Start date: 2025-04-01
• Primary completion: 2029-10-31
• Completion: 2029-10-31
• First posted: 2025-02-24
• Last updated: 2025-08-07

Locations

1 site across 1 country: Netherlands