NCT06840912

Electroencephalographic Biofeedback Therapy in Heroin Craving

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: Tanta University · Academic / Other
• Sex: Male
• Age: 20 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

The aim of this work is to assess the effectiveness of electroencephalography (EEG) biofeedback in management of heroin craving .

Detailed description

Substance use disorder is characterized by physiological dependence accompanied by the withdrawal syndrome upon abstinence from the drug, psychological dependence, tolerance, expressed in the escalation of the dose needed to achieve a desired euphoric state , and craving which is a pathological motivational state that leads to active drug-seeking behavior which leads to relapse . substance use disorder is a chronic, relapsing mental disease that results from the prolonged effects of drugs on the brain. Narcotic drugs addiction is recurrent and chronic mental illness with severe motivational disorders and loss of behavioral control. Craving is a penchant and persistent desire of drugs consumption, if it is not met, will have Psychological and physical sufferings, such as fatigue, anorexia, anxiety, insomnia, aggression, and depression. Also, voracity is very strong sense and urgent desiring to one thing, so that any possibility of focusing on something other than the asked subject is impossible. EEG biofeedback is an operant conditioning technique used to reinforce certain waves and inhibit others, in heroin patients, there is a decrease in mean alpha wave and SMR wave amplitude which persist and excess beta wave activity which abolished after 3 months of abstinence , increase in mean SMR wave amplitude lead to decrease impulsivity and improve attention , increase in alpha wave mean amplitude , decrease anxiety which accompany craving .

Conditions

• Electroencephalographic
• Biofeedback Therapy
• Heroin
• Craving

Interventions

Type	Name	Description
OTHER	Pharmacological in addition to electroencephalographic (EEG) biofeedback	Patients with heroin use disorder diagnosed according to DSM-5 criteria (Diagnostic and Statistical Manual of Mental Disorders 5th edition), treated by pharmacological in addition to electroencephalography (EEG) biofeedback after 3 months of abstinence.
DRUG	Pharmacotherapy	Patients with heroin use disorder taken as control group matching with patients group treated only by pharmacotherapy

Timeline

• Start date: 2023-02-01
• Primary completion: 2024-05-01
• Completion: 2024-05-01
• First posted: 2025-02-21
• Last updated: 2025-02-21

Locations

1 site across 1 country: Egypt