NCT06838598

Structural and Microbiological Characterization of Arterial Catheter Biofilm in ICU's Patients Using Optical Coherence Tomography

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 60 (estimated)
• Sponsor: Centre Hospitalier William Morey - Chalon sur Saône · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

29.3% of bacteremias in intensive care units (ICU) are linked to vascular devices, including 7.7% to arterial catheters, with an influence on both morbility and mortality. It is now accepted that biofilm as a role on bacterial development on inner surface of vascular devices but there is yet a lack of clinical relevant data documenting a causal relation between biofilm formation and bacteremias. The investigators assume that a better structural and microbiological characterization of arterial catheter biofilm in ICU patients could help preventing bacteremias or have a more specific treatment when it appears.

Conditions

• Biofilms
• Arterial Catheterization, Peripheral
• Bacteremia
• Tomography, Optical Coherence

Interventions

Type	Name	Description
OTHER	OCT-BIO-KTA cohort	Dynamic full-field optical coherence tomography (D-FF-OCT) analysis of arterial catheter sections before microbiological analysis of catheter biofilm

Timeline

• Start date: 2024-06-03
• Primary completion: 2027-11-01
• Completion: 2027-12-01
• First posted: 2025-02-20
• Last updated: 2026-03-18

Locations

2 sites across 1 country: France