NCT06836752

Effects of Yoghurt Consumption on Glucose Metabolism in Prediabetic Subjects

A Randomised, Open Label, Controlled, Parallel-group Study to Explore the Effects of 24 Weeks Intake of Yoghurt on Glucose Metabolism in Subjects at High Risk of Type 2 Diabetes Mellitus

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 8 (actual)
• Sponsor: Danone Global Research & Innovation Center · Industry
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to explore the effects of yoghurt consumption on glucose metabolism in prediabetic subjects.

Detailed description

Study population: the study population will consist of 60 (30 per group) subjects (men and women) at high risk of type 2 diabetes mellitus (T2DM), aged 18-65 years (inclusive), body mass index (BMI) 25.0 (inclusive) - 35.0 kg/m2 (exclusive), diagnosed with prediabetes, defined as fasting plasma glucose levels 100-125 mg/dL (5.6-6.9 mmol/L) (inclusive), randomised in a test and control group. Intervention comprises of two study periods: a refrain period from dairy products and pro-, pre- and synbiotic supplements in any form, for 2 weeks, followed by an intervention period of 24 weeks.

Conditions

• Prediabetes

Interventions

Type	Name	Description
OTHER	Yoghurt	250 g per day
OTHER	Milk	250 g per day

Timeline

• Start date: 2025-09-16
• Primary completion: 2025-10-15
• Completion: 2025-10-15
• First posted: 2025-02-20
• Last updated: 2026-01-12

Locations

1 site across 1 country: France