Trials / Recruiting
RecruitingNCT06835699
Psilocybin Brain Stimulation and Imaging Pilot Study
Open Label Psilocybin Brain Stimulation and Imaging Pilot Study
- Status
- Recruiting
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 15 (estimated)
- Sponsor
- Johns Hopkins University · Academic / Other
- Sex
- All
- Age
- 22 Years – 55 Years
- Healthy volunteers
- Accepted
Summary
This open-label pilot psilocybin administration study investigates the influence of psilocybin on brain function and cognitive control functions in clinically and psychiatrically healthy volunteers. Participants will undergo experimental drug administration sessions after careful screening and preparation. Participants will also have brain activity measured using electroencephalogram (EEG) also during non-invasive brain stimulation using Transcranial Magnetic Stimulation (TMS).
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Psilocybin 25 mgs | All participants will be administered 25 mg psilocybin and undergo TMS |
| DEVICE | TMS | All participants will be administered 25 mg psilocybin and undergo TMS |
Timeline
- Start date
- 2025-04-18
- Primary completion
- 2026-08-01
- Completion
- 2026-08-01
- First posted
- 2025-02-19
- Last updated
- 2025-07-28
Locations
1 site across 1 country: United States
Regulatory
- FDA-regulated drug study
- FDA-regulated device study
Source: ClinicalTrials.gov record NCT06835699. Inclusion in this directory is not an endorsement.