NCT06834243

Comparison of Intermittent Bolus Vs. Continuous Infusion PENG Block for Postoperative Pain in Hip Surgery

Comparison of Intermittent Bolus and Continuous Infusion Pericapsular Nerve Group Block on Recovery Quality and Analgesic Consumption: a Retrospective Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 82 (actual)
• Sponsor: Onur Baran · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

This retrospective study evaluates the effects of two different administration methods of the Pericapsular Nerve Group (PENG) Block on postoperative pain control, opioid consumption, and recovery in patients undergoing hip surgery. All patients in the study received: * PENG block via a catheter * Patient-Controlled Analgesia (PCA) with tramadol * Multimodal analgesia, including IV paracetamol and nonsteroidal anti inflammatory drugs (NSAIDs) as rescue analgesia The study compares two groups: 1. Intermittent Bolus Group: A researcher administered 20 mL of 0.25% bupivacaine every 4 hours. 2. Continuous Infusion Group: A pump delivered 5 mL/hour of 0.25% bupivacaine continuously. Both groups received the same total volume of local anesthetic over 24 hours. All PENG blocks were performed under ultrasound guidance at the end of surgery. This study aims to determine whether intermittent bolus or continuous infusion PENG block administration leads to better pain control, lower opioid consumption, and improved recovery outcomes.

Detailed description

Postoperative pain management after hip surgery remains a critical factor in recovery quality, opioid consumption, and overall patient outcomes. Among regional anesthesia techniques, the PENG Block is increasingly utilized for pain control due to its ability to provide effective analgesia while minimizing systemic opioid use. However, the optimal administration method of PENG block remains unclear. This retrospective cohort study evaluates the effectiveness of two different PENG block administration techniques in patients undergoing hip surgery: 1. Intermittent Bolus Group: A researcher manually administered 20 mL of 0.25% bupivacaine every 4 hours via a catheter placed under ultrasound guidance at the end of surgery. 2. Continuous Infusion Group: A pump delivered 5 mL/hour of 0.25% bupivacaine continuously via a catheter placed under ultrasound guidance at the end of surgery. Total local anesthetic volume over 24 hours was equal in both groups. Study Objectives: The primary objective is to compare intermittent bolus vs. continuous infusion PENG block administration in terms of: * Postoperative pain control (Visual Analog Scale) (VAS scores) * Total opioid consumption (morphine equivalent) * Time to first rescue analgesia * Quality of recovery (QoR-15 at 24 hours postoperative) Secondary outcomes include: * Postoperative nausea and vomiting (PONV) * Incidence of complications (hematoma, infection, nerve injury) This study aims to provide evidence on whether intermittent bolus or continuous infusion leads to better pain relief, reduced opioid consumption, and improved recovery in hip surgery patients.

Conditions

• Hip Surgery
• Postoperative Pain Management
• Pericapsular Nerve Group Block (PENG Block)
• Regional Anesthesia

Interventions

Type	Name	Description
PROCEDURE	Intermittent Bolus PENG Block	Patients received intermittent bolus administration of the Pericapsular Nerve Group (PENG) Block via a catheter. A researcher manually administered 20 mL of 0.25% bupivacaine every 4 hours over a 24-hour period.
PROCEDURE	Continuous Infusion PENG Block	Patients received continuous infusion of the Pericapsular Nerve Group (PENG) Block via a catheter. A pump delivered 5 mL/hour of 0.25% bupivacaine continuously over a 24-hour period.

Timeline

• Start date: 2023-11-15
• Primary completion: 2024-11-15
• Completion: 2024-11-15
• First posted: 2025-02-19
• Last updated: 2025-02-20

Locations

1 site across 1 country: Turkey (Türkiye)