Trials / Recruiting
RecruitingNCT06828380
A Study Comparing Immunotherapy Alone Versus Immunotherapy Combined With Radiotherapy in Patients With Hepatocellular Carcinoma (HCC) With Vascular Invasion
A Phase II Study of Immunotherapy With or Without Particle Beam Radiation Therapy in Patients With Advanced Hepatocellular Carcinoma Who Have Vascular Invasion: IOPT Study
- Status
- Recruiting
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 128 (estimated)
- Sponsor
- National Cancer Center, Korea · Other Government
- Sex
- All
- Age
- 19 Years
- Healthy volunteers
- Not accepted
Summary
In the present study, we aim to investigate the efficacy and safety of concurrent therapy of Immunotherapy based combination therapy and Radiotherapy in patients with advanced HCC showing macrovascular invasion.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| RADIATION | Particle beam radiation therapy | The prescribed dose and fractionation for proton therapy to the PTV will be determined by the physician, taking into account the dose-volume constraints of normal tissues such as the liver and bowel. |
Timeline
- Start date
- 2025-04-15
- Primary completion
- 2028-08-06
- Completion
- 2028-08-06
- First posted
- 2025-02-14
- Last updated
- 2025-12-26
Locations
2 sites across 1 country: South Korea
Source: ClinicalTrials.gov record NCT06828380. Inclusion in this directory is not an endorsement.