NCT06826534

At-Home Cardiac Rehabilitation for Adolescents at Risk for Heart Failure

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: Children's Hospital Los Angeles · Academic / Other
• Sex: All
• Age: 0 Years – 21 Years
• Healthy volunteers: Not accepted

Summary

The goal of this clinical trial is to explore the impact that an at-home cardio-oncology rehabilitation (CORE) may have on short-term cardiovascular fitness and psychosocial wellness in pediatric cancer survivors. The main question it aims to answer are * To evaluate the efficacy of an at-home CORE model on short-term cardiovascular fitness and psychosocial wellbeing in adolescent cancer survivors. * To evaluate the exercise adherence rate among adolescents at risk for heart failure and assess barriers to compliance. * To explore which specific CORE resources are of most value to patients in creating sustainable healthy lifestyle modifications. * Hypothesis: Pediatric cancer survivors who implement exercise and dietary recommendations will demonstrate improvement in cardiovascular fitness and general wellness. A multidisciplinary team approach can facilitate adherence to a moderately rigorous exercise prescription, and thus enhance the health benefits of a CORE program at CHLA. Participants will undergo cardiovascular studies and a quality-of-life survey prior to exercise intervention, and at the end of the 6-month study period.

Conditions

• Cardiovascular Complication
• Chemotherapeutic Toxicity

Interventions

Type	Name	Description
BEHAVIORAL	Cardio-oncology rehabilitation	Least 60 minutes of physical activity each day including vigorous-intensity and strengthening activities at least 3 days per week

Timeline

• Start date: 2023-10-20
• Primary completion: 2025-12-31
• Completion: 2025-12-31
• First posted: 2025-02-14
• Last updated: 2025-02-14

Locations

1 site across 1 country: United States