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Trials / Completed

CompletedNCT06824051

A Study of Orforglipron (LY3502970) in Adult Participants With Obesity or Overweight

A Phase 1, Double-blind, Two-arm, Mechanism of Action Study to Investigate the Effect of Orforglipron on Body Composition in Adult Participants With Obesity or Overweight, Without Diabetes

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
120 (actual)
Sponsor
Eli Lilly and Company · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The main purpose of this study is to see how orforglipron affects the amount of body fat compared with placebo in participants with obesity or overweight. Participation in the study will last approximately 8 months.

Conditions

Interventions

TypeNameDescription
DRUGOrforglipronAdministered orally
DRUGPlaceboAdministered orally

Timeline

Start date
2025-02-17
Primary completion
2026-01-26
Completion
2026-01-26
First posted
2025-02-13
Last updated
2026-02-25

Locations

4 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT06824051. Inclusion in this directory is not an endorsement.

A Study of Orforglipron (LY3502970) in Adult Participants With Obesity or Overweight (NCT06824051) · Clinical Trials Directory