NCT06821399

Optimization and Evaluation of the Diagnosis and Treatment System for Diabetic Retinopathy in Type 2 Diabetes Mellitus

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 2,920 (estimated)
• Sponsor: Yufan Wang · Academic / Other
• Sex: All
• Age: 20 Years – 79 Years
• Healthy volunteers: Not accepted

Summary

This study aims to integrate clinical indicators and features of fundus images, combined with metabolomics, to construct an early warning model for diabetic retinopathy (DR) in type 2 diabetes. By combining clinical indicators with metabolomics, the investigators aim to establish a precise DR typing model based on the age of diabetes onset (early-onset diabetes, late-onset diabetes) and based on the coexistence with two types of diabetic macrovascular complications. A multidisciplinary collaboration will be conducted for comprehensive management of DR to control the progression of moderate-stage DR. Cloud-based patient rooms combined with continuous glucose monitoring (CGM) will further explore the role of integrated diabetes retinopathy ward management models in the management of patients undergoing diabetes retinopathy surgery, pioneering a new model for the management of advanced DR.

Conditions

• Diabetes
• Diabetic Retinopathy
• Type 2 Diabetes Mellitus (T2DM)

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Fundus Examination	Performing fundus photography on patients to assess the progression of diabetic retinopathy (DR).
DIAGNOSTIC_TEST	Metabolomics analysis	Conduct metabolomics testing at enrollment.

Timeline

• Start date: 2025-02-01
• Primary completion: 2025-08-31
• Completion: 2028-07-31
• First posted: 2025-02-12
• Last updated: 2025-05-15

Locations

3 sites across 1 country: China