NCT06821386

N-Care Project: Enhancing Asian-Pacific Collaboration

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 70 (estimated)
• Sponsor: National Taiwan University Hospital · Academic / Other
• Sex: All
• Age: 18 Months
• Healthy volunteers: Not accepted

Summary

Through Asian-Pacific multinational collaboration, we aim to utilize third-generation genome sequencing to rapidly diagnose genetic diseases in critically ill infants and young children, achieving the goal of early diagnosis for targeted treatment.

Detailed description

A group of individuals with specific characteristics was selected. Genetic studies were arranged for participants who provided their consent.

Conditions

• Whole Genome Sequencing
• Genetic Disease
• Critical Care, Intensive Care
• Nanopore Sequencing

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Genetic study with nanopore sequencing	The study targets critically ill children under 18 months of age, employing third-generation genome sequencing technology to complete long-read sequencing within 8-11 days, analyzing single nucleotide variants, small insertions/deletions, and structural variations. Through this research, we aim to enhance diagnostic accuracy, enabling ICUs to provide personalized and precision care and treatment based on genetic information, thereby ensuring a greater level of health security for these children. We only draw 3-5cc whole blood once for exam.

Timeline

• Start date: 2025-02-17
• Primary completion: 2025-12-31
• Completion: 2032-12-31
• First posted: 2025-02-12
• Last updated: 2025-02-20

Locations

1 site across 1 country: Taiwan