NCT06820931

Indicators and Evaluation of Efficacy of Yin-nourishing and Fire-reducing Chinese Medicine for Girls With Rapid Progression of Early Puberty

• Status: Recruiting
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 80 (estimated)
• Sponsor: Children's Hospital of Fudan University · Academic / Other
• Sex: Female
• Age: 8 Years – 9 Years
• Healthy volunteers: Not accepted

Summary

1\. Evaluate whether AMH and SHBG have differential expression before and after the diagnosis of rapid and slow progression types of early puberty and whether this difference has a predictive effect on the rapid progression type. 2. Assess the therapeutic effect of nourishing yin and purging fire traditional Chinese medicine on girls with rapid progression type of early puberty providing a standardized clinical basis for the formulation of diagnostic and treatment guidelines (or protocols) for the rapid progression type of early puberty using traditional Chinese medicine

Conditions

• Puberty Changes

Interventions

Type	Name	Description
DRUG	Xuandi Ziyin Mixture	Treatment is given only with the hospital preparation 'Xuandi Ziyin Mixture' with a dosage of 30ml per administration three times a day.

Timeline

• Start date: 2025-01-01
• Primary completion: 2025-12-31
• Completion: 2026-02-28
• First posted: 2025-02-11
• Last updated: 2025-02-11

Locations

1 site across 1 country: China