NCT06820853

Single-shot Versus Slow Infusion Interscalene Block and Its Impact on Diaphragmatic Function in Patients Undergoing Shoulder Surgery.

Single-shot Versus Slow Infusion Interscalene Block and Its Impact on Diaphragmatic Function in Patients Undergoing Shoulder Surgery, a Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (actual)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

Interscalene brachial plexus block is a commonly chosen anesthetic technique for shoulder and proximal arm surgery yet it carry several risks including phrenic nerve block. Researchers assumed that slow administration of local anesthetic would reduce incidence of phrenic nerve block

Detailed description

patients will be randomly allocated into one of 2 groups ( single shot group) and slow administration group . single shot will receive a 10 ml bolus of 0.5% bupivacaine the other group will receive 10 ml 0.5 % bupivacaine over 10 minutes (at a rate of 1ml/minute) using syringe pump An experienced operator who will be blinded to method of administration will conducted diaphragmatic excursion of ipsilateral hemidiaphragm using curved probe at baseline and at 10 minutes interval for 30 minutes Complete phrenic will be defined as 75% or more reduction in DE, while partial failure as 25%-50% reduction in DE

Conditions

• Brachial Plexus Blockade

Interventions

Type	Name	Description
DEVICE	Diaphragmatic excursion evaluation	They will receive 10 ml of 0.5% bupivacaine over 10 minutes

Timeline

• Start date: 2025-02-16
• Primary completion: 2025-05-19
• Completion: 2025-05-19
• First posted: 2025-02-11
• Last updated: 2025-05-22

Locations

1 site across 1 country: Egypt