NCT06820125

Isolated Versus Combined Cognitive and Motor High-tech Rehabilitation

Isolated Versus Combined Cognitive and Motor High-tech Rehabilitation in Patients with Multiple Sclerosis

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 48 (estimated)
• Sponsor: Universita di Verona · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The first aim of this project is to investigate the effects of different high-tech neurorehabilitation interventions (cognitive, motor, and combined cognitive-motor) on both cognitive and motor disability outcomes in people with multiple sclerosis (MS). The second aim is to identify the cognitive and motor profiles of MS patients who benefit the most from either the combined cognitive-motor rehabilitation intervention or the isolated cognitive or motor treatments.

Conditions

• Rehabilitation
• Multiple Sclerosis
• Cognitive Deficit
• Motor Deficits

Interventions

Type	Name	Description
DEVICE	Cognitive rehabilitation: CG group	60 minutes of cognitive training with a computerized device
DEVICE	Motor rehabilitation: MG group	60 minutes of robot-assisted gait training with the G-EO System
DEVICE	Combined rehabilitation: CbG group	30 minutes of cognitive training with a computerized device + 30 minutes of robot-assisted gait training with the G-EO System. To mitigate the effects of fatigue in sequential training, the patients included in this group will undergo the cognitive (treatment CG) and motor (treatment MG) sessions in a counterbalanced order (half of the participants will follow the CG-MG sequence, and the other half will follow the MG-CG sequence). Five-minute breaks will be provided between the cognitive and motor sessions.

Timeline

• Start date: 2023-07-05
• Primary completion: 2023-07-05
• Completion: 2026-07-05
• First posted: 2025-02-11
• Last updated: 2025-02-11

Locations

1 site across 1 country: Italy