NCT06819436

Effect of Dexamethasone on Post-spinal Hypotension

Effect of Dexamethasone on Post-spinal Hypotension in Geriatric Patients Undergoing Orthopaedic Surgery at Tertiary Care Hospital Karachi.

• Status: Recruiting
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 170 (estimated)
• Sponsor: Shaheed Mohtarma Benazir Bhutto Institue of Trauma · Academic / Other
• Sex: All
• Age: 65 Years – 85 Years
• Healthy volunteers: Accepted

Summary

The goal of this clinical trial is to learn if intravenous dexamethasone is effective for prevention of post spinal hypotension in geriatric population undergoing orthopedic surgeries. The main question aim to answer is: Does intravenous dexamethasone in participants undergoing orthopedic procedures of lower limb under spinal anesthesia prevents post spinal hypotension? Researchers are comparing two groups of participants * Participants in (Dexamethasone Group) Group D are receiving intravenous dexamethasone 8mg preoperatively * Participants in (Placebo Group) Group P are receiving placebo preoperatively.

Conditions

• Post Spinal Anaesthesia Hypotension
• Geriatric Population
• Orthopedic Surgeries

Interventions

Type	Name	Description
DRUG	Dexamethasone	Intravenous dexamethasone 8mg given to participants before spinal anesthesia
OTHER	Placebo	Intravenous placebo given to the participants before spinal anesthesia

Timeline

• Start date: 2025-02-01
• Primary completion: 2025-04-01
• Completion: 2025-05-01
• First posted: 2025-02-11
• Last updated: 2025-02-11

Locations

1 site across 1 country: Pakistan