NCT06816511

Preliminary Explorative Study of Magnetic Resonance-Guided Focused Ultrasound Surgery in Refractory Obsessive-Compulsive Disorder Patients

• Status: Enrolling By Invitation
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (estimated)
• Sponsor: National Taiwan University Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The goal of this clinical trial is to evaluate If magnetic resonance-guided focused ultrasound works to treat refractory obsessive-compulsive disorder in adults. The main questions it aims to answer are: * What effectiveness does the magnetic resonance-guided focused ultrasound bring to the participants during study period? * What side effects do the participant have when treated with magnetic resonance-guide focused ultrasound? Participants will: * Finish scales to evaluate participants' level of cognitive function, depression and Compulsiveness. * Receive the treatment of magnetic resonance-guided focused ultrasound * Take the fMRI brain scanning before and after the treatment * Recovering

Conditions

• Obsessive-Compulsive Disorder (OCD)

Interventions

Type	Name	Description
PROCEDURE	magnetic resonance-guided focused ultrasound surgery, MRgFUS	Magnetic Resonance-Guided Focused Ultrasound Surgery The clinical symptoms, brain imaging, and cognitive function status were followed up for 2 years before and after surgery.

Timeline

• Start date: 2024-01-01
• Primary completion: 2026-12-31
• Completion: 2026-12-31
• First posted: 2025-02-10
• Last updated: 2026-03-17

Locations

1 site across 1 country: Taiwan