NCT06815341

Risk Factors for Sub Mucosal Fibrosis During Achalasia Cardia: A Prospective Study

Risk Factors for Sub Mucosal Fibrosis During Achalasia Cardia

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 339 (estimated)
• Sponsor: Asian Institute of Gastroenterology, India · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: —

Summary

Classification for Stasis Esophagitis: Grade I Grade II Grade III Vascular pattern Obscured Obscured Obscured Mucosal thickening No Yes Yes Ulceration No Yes Yes Nodularity No No Yes

Detailed description

Predictors of Submucosal Fibrosis: Various factors were analysed for prediction of SMF including age, gender, stasis esophagitis, type of achalasia, duration of disease, lower esophageal sphincter pressure (LESP), height of barium column on barium esophagogram and severity of symptoms (Eckardt score). Esophageal mucosa was graded for the severity of stasis esophagitis (grade I to grade III) based on vascular pattern, mucosal thickening, ulceration and nodularity. SMF was graded (I minimal, II moderate, III severe) according to mucosal lift, difficulty in entry, density of SM fibers, separation of mucosa and muscle.

Conditions

• Esophagus Disorder

Timeline

• Start date: 2021-08-14
• Primary completion: 2025-02-20
• Completion: 2025-04-20
• First posted: 2025-02-07
• Last updated: 2025-02-11

Locations

2 sites across 1 country: India