NCT06815302

TURN-IT FOG: Improving Turning and Freezing of Gait in People With PD

TURN-IT FOG: A Novel Intervention to Improve Turning in People With PD and Freezing of Gait

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Oregon Health and Science University · Academic / Other
• Sex: All
• Age: 50 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The goals of this clinical trial are to 1) learn how two different rehabilitation interventions for PD can reduce Freezing of Gait (FOG) in people with Parkinson's disease, as assessed by patients, clinicians, and wearable sensors, and 2) to explore whether two different rehabilitation intervention can reduce FOG and improve daily life mobility in people with FOG sufficiently to justify a clinical trial. Participants will: * Be randomly assigned to one of two intervention groups (turning-focused agility exercise or strength-based exercise) * Have one-on-one training sessions three times per week for 6 weeks * Perform in-lab assessments before beginning and after completing the study intervention * Use wearable mobility sensors during daily life to measure their walking and balance

Conditions

• Parkinson Disease
• Freezing of Gait Symptoms in Parkinson Disease

Interventions

Type	Name	Description
BEHAVIORAL	Experimental intervention	Specific participant procedures in experimental and active control interventions are simplified to preserve study blinding.
BEHAVIORAL	Active intervention	Specific participant procedures in experimental and active control interventions are simplified to preserve study blinding.

Timeline

• Start date: 2025-06-02
• Primary completion: 2026-12-31
• Completion: 2027-06-30
• First posted: 2025-02-07
• Last updated: 2025-07-28

Locations

3 sites across 2 countries: United States, Brazil