NCT06813963

Minoxidil for Treating White Hair: A Randomized Controlled Trial

A Randomized, Double-Blind, Multicenter, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Minoxidil in the Repigmentation of White Hair in Adults

• Status: Recruiting
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Southern Medical University, China · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The goal of this clinical trial is to evaluate whether topical Minoxidil can restore hair pigmentation in individuals with non-pathological graying hair. The study population includes male and female participants aged \[18to65\] who have non-pathological graying of hair, meaning their graying is not due to any underlying medical conditions. The main questions it aims to answer are: Does topical Minoxidil improve hair pigmentation in individuals with non-pathological graying hair? What medical problems do participants have when topical use minoxidil? Researchers will compare participants receiving topical Minoxidil to those receiving a placebo to determine whether Minoxidil has a significant effect on restoring hair pigmentation. Participants will: Topical use minoxidil or a placebo twice a day for 12 months Visit the clinic once every months for checkups and tests Report any adverse effects or changes in hair characteristics throughout the study.

Conditions

• Grey Hair

Interventions

Type	Name	Description
DRUG	Topical Minoxidil（5%） to the scalp.	The patient will apply 5% Minoxidil topical solution to the scalp twice daily, with 7 sprays (approximately 1 mL) per application, for a duration of 12 months.
DRUG	Placebo	The patient will apply placebo to the scalp twice daily, with 7 sprays (approximately 1 mL) per application, for a duration of 12 months.

Timeline

• Start date: 2025-02-15
• Primary completion: 2026-02-15
• Completion: 2026-12-15
• First posted: 2025-02-07
• Last updated: 2025-09-05

Locations

2 sites across 1 country: China