NCT06812000

Post-stroke Seizure and Epilepsy Following Thrombolytic Therapy

Investigation of Incidence Rate of Post-stroke Seizure and Post-stroke Epilepsy in Patients Under Treatment With Alteplase and Correlated Factors

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 199 (actual)
• Sponsor: Mazandaran University of Medical Sciences · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This retrospective cohort study was conducted by reviewing the records of consecutive patients referred to Bu Ali Sina Hospital from 2016 to 2023, who were hospitalized with a diagnosis of ischemic stroke. The records of all patients treated with intravenous alteplase during the above period were extracted, and the relevant characteristics were recorded in a questionnaire. In each year, patients with ischemic stroke who were not treated with alteplase but were hospitalized at the Bu Ali Center were selected in a similar number to patients who received alteplase in the same year, and the relevant information was extracted from their records and recorded in a questionnaire. The incidence of post-stroke seizures and epilepsy was determined in both groups, and the factors associated with their incidence were studied and compared.

Conditions

• Post-stroke Seizure
• Post-stroke Epilepsy
• Thrombolytic (t-PA) Treatment

Timeline

• Start date: 2024-04-14
• Primary completion: 2025-01-12
• Completion: 2025-01-12
• First posted: 2025-02-06
• Last updated: 2025-02-06

Locations

1 site across 1 country: Iran