Trials / Not Yet Recruiting
Not Yet RecruitingNCT06809062
ApoE Genotyping Analysis in Patients with Suspected Non-haemorrhagic Amyloid Angiopathy
- Status
- Not Yet Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 100 (estimated)
- Sponsor
- Centre Hospitalier Universitaire de Nīmes · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Ischaemic microangiopathic features have recently been incorporated into the criteria for cerebral amyloid angiopathy (CAA). ApoE genotyping (presence of the E4 allele) is routinely used to help determine the aetiology of a haemorrhagic microangiopathy found on MRI. Chronic ischaemic disease in CAA is characterised by the presence of : * multispot pattern on the FLAIR sequence * severe periventricular FLAIR hypersignals with posterior predominance The main aim of this study was therefore to analyse the frequency of the presence of one (or two) E4 allele(s) on ApoE genotyping in patients with suspected CAA based on ischaemic MRI involvement with a typical radiological pattern.
Conditions
Timeline
- Start date
- 2025-02-01
- Primary completion
- 2025-12-31
- Completion
- 2025-12-31
- First posted
- 2025-02-05
- Last updated
- 2025-02-05
Source: ClinicalTrials.gov record NCT06809062. Inclusion in this directory is not an endorsement.