NCT06806566

Assessment of a Carvacrol-loaded Absorbable Gelatin Sponge Used as a Palatal Dressing Following Free Gingival Graft Harvesting.

Clinical Evaluation of Carvacrol Loaded Absorbable Gelatin Sponge as a Palatal Bandage After Free Gingival Graft Harvesting .

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: British University In Egypt · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

To evaluate the effect of carvacrol loaded to absorbable gelatin sponge as a palatal bandage on the palatal donor site in post-operative pain reduction after free gingival graft harvesting

Conditions

• Palatal Wound

Interventions

Type	Name	Description
OTHER	Carvacrol	1-absorbable gelatine sponge soaked in carvacrol oil placed in the palatal donor site. Procedure: The palatal sites will be anaesthetized with 0.3 ml of a solution of 4% Articaine and 0.001% Adrenalin. Graft harvesting will be performed by basic surgical techniques previously described by Miller (1982). A rectangular shaped piece of mucosa will be harvested from the area of the hard palate by a split-thickness dissection. The graft will then be used as it on the recipient bed. The graft dimensions will be recorded (width and length). Denuded palatal area will then be protected using a carvacrol loaded absorbable gelatin sponge (test group)
OTHER	Gelatin Sponge Sheet	Absorbable gelatin sponge placed in the palatal donor site Procedure: The palatal sites will be anaesthetized with 0.3 ml of a solution of 4% Articaine and 0.001% Adrenalin. Graft harvesting will be performed by basic surgical techniques previously described by Miller (1982). A rectangular shaped piece of mucosa will be harvested from the area of the hard palate by a split-thickness dissection. The graft will then be used as it on the recipient bed. The graft dimensions will be recorded (width and length). Denuded palatal area will then be protected using a absorbable gelatin sponge(control group).

Timeline

• Start date: 2024-02-01
• Primary completion: 2025-05-01
• Completion: 2025-05-01
• First posted: 2025-02-04
• Last updated: 2026-04-06

Locations

1 site across 1 country: Egypt