NCT06804434

Impact of Intraoperative Non-invasive Analgesia Monitoring Using Nociception Level Index on Patient Management

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 160 (estimated)
• Sponsor: Osoian Cristiana · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This prospective randomised clinical trial aims to assess the impact of intraoperative nociception monitoring using NOL on anesthetic management during major abdominal surgery. Additionally, the study will objectively evaluate using NOL how intravenous lidocaine administration, influences opioid requirements and the effect of this multimodal approach on early postoperative outcomes. The investigators hypothesize that NOL-guided intraoperative opioid administration reduces both intraoperative and postoperative opioid use, positively influencing 24-hour outcomes. Furthermore, the addition of intraoperative lidocaine in NOL-guided analgesia may further decrease opioid consumption.

Conditions

• Pain
• Anesthesia
• Perioperative Care

Interventions

Type	Name	Description
DRUG	Lidocaine Intravenous Infusion	intravenous lidocaine 10 mg/ml continuous infusion
DEVICE	NOL	Intraoperative Nociception Level index monitoring and guided analgesia

Timeline

• Start date: 2023-05-18
• Primary completion: 2026-02-01
• Completion: 2026-02-01
• First posted: 2025-02-03
• Last updated: 2025-02-03

Locations

1 site across 1 country: Romania