Trials / Not Yet Recruiting
Not Yet RecruitingNCT06801353
A Cohort Study on Biomarkers to Predict the Efficacy of Biologics for Chronic Rhinosinusitis with Nasal Polyps
- Status
- Not Yet Recruiting
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 90 (estimated)
- Sponsor
- Beijing Tongren Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
Recently, several biologic therapies have become available for treating chronic rhinosinusitis with nasal polyps (CRSwNP). However, not every patient responds to these treatments. This clinical trial aims to develop a non-invasive predictive model to help determine how effective IL-4Rα targeted monoclonal antibody therapy will be for individuals with CRSwNP.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BIOLOGICAL | Stapokibart | Stapokibart subcutaneously every two weeks |
| DRUG | Mometasone Furoate Nasal Spray (MFNS) | mometasone furoate nasal spray 200 μg once daily |
Timeline
- Start date
- 2025-02-01
- Primary completion
- 2025-12-01
- Completion
- 2026-07-01
- First posted
- 2025-01-30
- Last updated
- 2025-02-06
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT06801353. Inclusion in this directory is not an endorsement.